In molecular biology, slow PCR extension cycles can quickly become a major bottleneck in daily laboratory operations. Whether you're performing high-throughput screening, molecular diagnostics, or amplifying precious low-abundance targets, you need a DNA polymerase that delivers exceptional speed without compromising sensitivity and fidelity.
Meet ZipTaq DNA Polymerase—the fastest and most sensitive enzyme offered by DNA Polymerase Technology. Engineered for rapid amplification and robust performance, ZipTaq helps streamline PCR workflows while maintaining outstanding sensitivity across a wide range of applications.
What Makes ZipTaq Different?
ZipTaq is engineered with proprietary mutations that significantly increase its extension rate compared with wild-type Taq and many commercially available Taq DNA polymerases. In addition to faster amplification, ZipTaq demonstrates enhanced performance with samples containing trace amounts of PCR inhibitors and very low template copy numbers.
Key Features & Benefits
- Fast PCR Cycling
ZipTaq is the fastest polymerase in our product portfolio, allowing dramatically shorter PCR run times, faster turnaround, and maximized thermal cycler throughput. - Exceptional Sensitivity
Optimized for robust amplification from extremely low amounts of target DNA, ZipTaq delivers reliable results even with challenging, low-copy-number samples. - Outstanding Blood Tolerance
When used with our PCR Enhancer Cocktail (PEC), ZipTaq can amplify DNA directly from reactions containing up to 40% whole blood, making it an excellent choice for direct PCR applications without sample preparation. - TaqMan Probe Compatible
ZipTaq integrates seamlessly into quantitative PCR (qPCR) workflows utilizing hydrolysis (TaqMan) probes. - Optimized Proprietary Buffer
The enzyme is supplied with a specially formulated 10X ZipTaq Reaction Buffer designed to maximize amplification speed, sensitivity, and overall performance.
Flexible Solutions for Every PCR Application
The ZipTaq product family includes specialized formulations to meet a variety of research and diagnostic needs:
- Hot Start ZipTaq
Features an aptamer-based hot-start mechanism that suppresses polymerase activity at ambient temperatures, minimizing nonspecific amplification and primer-dimer formation. - ZipTaq LA
Combines ZipTaq's rapid extension rate with proofreading activity for long-range, high-accuracy PCR. - Hot Start ZipTaq LA
Integrates hot-start technology with long-range, high-fidelity amplification for demanding applications. - Lyoph-Ready ZipTaq
Formulated with reduced glycerol content to facilitate lyophilization, making it ideal for point-of-care diagnostic kit development. - 5X ZipTaq PCR Kit
A convenient all-in-one master mix alternative containing ZipTaq DNA Polymerase, optimized reaction buffer, and dNTPs for quick, reproducible PCR setup.
Ready to Accelerate Your PCR Workflows?
ZipTaq is available in convenient package sizes starting at 125 µL, sufficient for approximately 500–1,000 x 25 µL PCR reactions, with pricing at $350.00.
To learn more, download the technical datasheet, or place an order, visit the official ZipTaq product page (https://www.klentaq.com/products/ziptaq) or contact our technical support team at enzyme@klentaq.com.
Experience the speed, sensitivity, and reliability of ZipTaq—and discover how faster PCR can improve your laboratory productivity without compromising performance.